Lois Smith

as Hanna

as Elizabeth Crawford (voice)

as Lydia

as Trudie Ferreira

as Helen

as Delores Feinn(1 ep)

as Betty

as Beverly(1 ep)

as Upshur 'Maw' Clampette

as Iris Lefferts(1 ep)

as Doris 'Mama' Boone(3 eps)

as Aunt Butch

as Harper Pitt

as The Grande Dame

as Mimi Waldenstock(2 eps)

as Deirdre 'Dippy' Jones(1 ep)

as Wrong Nana(1 ep)

as Sister Sarah Joan

as Marjorie

as Miriam

as Mrs. Glenn

as Reverend Ethel Landry(2 eps)

as Mrs. Hanson(2 eps)

as Belinda Lacroix(1 ep)

as Margaret Conlon

as Mrs. Gunther(1 ep)

as Self

as The Youngest Daughter (later)

as Claire(1 ep)

as Lucy Game(1 ep)

as Dolores(2 eps)

as Betty Turner(1 ep)

as Ruth(7 eps)

as Aunt Mel

as Mom

as Mrs. Portman

as Lois Blair

as Lenore

as Adele Stackhouse(14 eps)

as Belle

as Abby

as Elsie(1 ep)

as Dr. Imberman

as Helen Bessolo

as Elizabeth

as Social Worker

as Inge (as an older woman)

as Self

as Mrs. Dickerson(1 ep)

as Ellie Silverstein

as Allison Scavo(2 eps)

as Rose Sinclair(1 ep)

as Reverend Anna Howard Shaw

as Helen

as Fannie(1 ep)

as Ma Adams

as Helen Rounds

as Dr. Iris Hineman

as Lucy Thompson

as Betty Bennett(1 ep)

as Mother

as Mother(1 ep)

as Helen Jackson

as Ginger

as Rebecca Tolliver(1 ep)

as Miss Maude(2 eps)

as Mrs. Ferriter

as Julia

as Libby(1 ep)

as Mary Beth Berluti(1 ep)

as Luluna

as Aunt Meg

as Helen's Mother

as Sophia

as Madge Wallace Gates

as Mildred Mancini(1 ep)

as Gracie(4 eps)

as Orna

as Moira(1 ep)

as D-Fens' Mother

as Lou Wheaton

as voice

as Lureen

as Mrs. Bell

as Mama Threadgoode

as Alice Todd

as Margaret(2 eps)

as Ma Joad

as (voice)

as Mrs. Tannen(3 eps)

as Brontë's Mother

as Eunice Varick(1 ep)

as Self

as (voice)(2 eps)

as Mrs. Nelson

as Martha

as Sara

as Sarah

as Mary Neal

as Marie Ganucci(1 ep)

as Dorothy Hermes(1 ep)

as Helen Giles

as Mrs. Prescott

as Mare Spofford

as Clara(2 eps)

as Ma Joad(1 ep)

as Mrs. Carnahan

as Bertha Dorset

as Kathy

as Cornelia

as Mrs. Axman

as Sara(1 ep)

as Anita Cunningham

as Elinore

as Anne Starr

as Woman (segment "Talk to Me Like the Rain and Let Me Listen")

as Partita Dupea

as Jane Aldridge

as Evelyn

as Evelyn(1 ep)

as Libby Clayton(1 ep)

as Esther Terranova(1 ep)

as Dana(1 ep)

as Lucy Brown(1 ep)

as Hilda

as Cindy(1 ep)

as Dawn Garrison(1 ep)

as Self - Nominee / Performer(1 ep)

as Self - Nominee(1 ep)

as Spurs O'Brien

as Anne

as Jeannie(1 ep)

as Jenny Musgrave(1 ep)

as Lisa Molloy(1 ep)