Danielle Panabaker
Dr. Caitlin Snow / Frost, Dr. Caitlin Snow, Khione, Dr. Caitlin Snow / Killer Frost
Candice Patton
Iris West-Allen, Iris West
Tom Cavanagh
Dr. Harrison Wells, Eobard Thawne / Reverse-Flash / Timeless Wells, Harrison 'Nash' Wells, Harrison 'Sherloque' Wells, Harrison 'Harry' Wells, Harrison Wells, Eobard Thawne, Eobard Thawne / Reverse-Flash, Harrison Wells / Timeless Wells, Eobard Thawne / Reverse-Flash / The Flash, Harrison 'H.R.' Wells, Various Versions of Harrison Wells, Eobard Thawne / Reverse-Flash / Negative Reverse-Flash
Carlos Valdes
Cisco Ramon / Mecha-Vibe, Cisco Ramon, Cisco Ramon / Vibe
Hartley Sawyer
Ralph Dibny / Elongated Man
Patrick Sabongui
Mirror Chief David Singh, David Singh
Keiynan Lonsdale
Wally West / Kid Flash, Wally West
Jessica Parker Kennedy
Nora West-Allen / XS, Mystery Girl
Rick Cosnett
Eddie Thawne, Dr. Malcolm Gilmore
Michelle Harrison
Nora Allen (voice), Nora Allen, Joan Williams / Speed Force Nora, Joan Williams, Speed Force Nora
Morena Baccarin
Gideon (voice) (uncredited)
John Wesley Shipp
Barry Allen / The Flash (Earth 90), Henry Allen, Jay Garrick / The Flash
Jon Cor
Mark Blaine / Chillblaine
Stephanie Izsak
Officer Daisy Korber, Captain Daisy Korber, Uni #1
Victoria Park
Kamilla Hwang, Mirror Kamilla Hwang, Kamilla Hwang / Mirror Kamilla Hwang
Violett Beane
Jesse Wells / Jesse Quick, Jesse Wells
Teddy Sears
Hunter Zolomon / Zoom, Jay Garrick, Jay Garrick / Hunter Zolomon, Jay Garrick / Zoom
Kim Suzanne Engelbrecht
Marlize DeVoe / The Mechanic
Wentworth Miller
Leonard Snart / Captain Cold, Leonard A.I. (voice), Leo Snart / Citizen Cold
Tobin Bell
Doctor Alchemy / Savitar (voice) (uncredited), Savitar (voice) (uncredited), Doctor Alchemy (voice) (uncredited), Savitar (voice)
Robbie Amell
Ronnie Raymond / Firestorm, Ronnie Raymond / Deathstorm, Ronnie Raymond / Deathstorm (voice)
Neil Sandilands
Clifford DeVoe / The Thinker
Christian Magby
Deon Owens / Negative Deon Owens, Deon Owens
Victor Garber
Prof. Martin Stein (voice), Dr. Martin Stein, Digsy's Husband
Efrat Dor
Eva McCulloch / Mirror Monarch
Sendhil Ramamurthy
Dr. Ramsey Rosso / Bloodwork
